Down Syndrome

By: Mallory and Taylor

Biological Cause

- Results from one extra chromosome on the 21st pair.

- Only inherited type is translocation down syndrome, about half of translocation cases are inherited.

http://www.chkd.org/HealthLibrary/Content.aspx?pageid=P02153

Picture caption: Karyotype (http://www.hhmi.org/news/quake20081006.html)

Physical Characteristics

Low muscle tone
Flattened facial features
Hyper-flexibility
Single, deep crease on hand

http://children.webmd.com/understanding-down-syndrome-symptoms

Symptoms

heart disease
thyroid problems
leukemia
immune system problems
hearing problems
eye problems
seizures
bone, joint, muscle problems
mental retardation

http://www.mayoclinic.com/health/down-syndrome/DS00182/DSECTION=complications

Picture caption: http://www.livestrong.com/article/560559-socialization-of-teens-with-down-syndrome/

Research

-Current research with mice going on
-Least funded genetic condition
-Most common chromosomal disorder
-3 types

Treatments

No know cure, but some things that help are:
-regular checkups
-screenings
-medication
-surgery

http://down-syndrome.emedtv.com/down-syndrome/treatment-for-down-syndrome.html