Cystic Fibrosis

By: Ivy Young

Definition:

Cystic Fibrosis is a genetic disorder that damages the lungs, digestive system, sweat glands, and male fertility by causing thick mucus build up.

Symptoms and Signs:

Respiratory:

  • Wheezing
  • Loss of Breath
  • Constant cough
  • Difficulty Exercising
  • Lung Infections
  • Cold-like pains

Digestive:

  • Foul scented stool
  • Poor weight gain and growth
  • Intestinal Blockage
  • Extreme Constipation

What causes Cystic Fibrosis?

CF is a recessive disorder that is autosomal, and is located on Chromosome 7. You inherit it from your parents!

Who has it?

Mainly Caucasian people inherit the disorder and is it equally common among women and men. 75% of people are diagnosed by 2, and have a life span of about 37.

  • 1 in 2500- 3500 Caucasian
  • 1 in 17000 African Americans
  • 1 in 90000 Asians

Diagnosis and Treatment:

The diagnosis is made commonly with sweat tests and genetic tests.

CF is treated with airway clearance, inhaled medicine, and enzyme supplements with meals.


CF Spotlight:

Living with Cystic Fibrosis - Lauren's Story

Research:

1998 - CF gene was discovered

1993 - The first gene therapy was given

Now, researchers of different disciplines collaborate. These researchers use new knowledge of the CF gene to design new therapies.