Endocrine System Communication

By : Triet Nguyen , Aaron Celeskey , Matthew Xavier

Endocrine Signals


Paracrine signal happen when cell secrete chemical mediator that are destroyed , absorbed , or immobile quickly . They usually target cell that is near .


Usually paracrine system involved many different type of cell however some cell are able to create signal that them self respond to called Autocrine signal .


Endocrine signal maintain homeostasis , regulates growth and development and target cell through the bloodstream . Signal from distant cell that originate from endocrine cell , have a long lasting effect but usually slow response .

How does our body know what to secrete and when?

The endocrine system works closely with the nervous system. Some theorize that the endocrine system evolved from the nervous system from nervous system cells being secreted into the bloodstream
The gland that starts the communication chain is the hypothalamus when it responds to signal from the nervous system. It creates a chemical that controls the pituitary gland. The pituitary gland ( master gland ) influences may other glands in the endocrine system. The pituitary gland is broken down into two major parts the anterior and posterior lobe. The signals from the hypothalamus go into the anterior lobe and them the pituitary gland secretes hormones into the bloodstream. These hormones then are sent to the various other organs.

Feedback Loops

When blood glucose levels rise, insulin is secreted by the pancreas, lowering blood glucose by increasing its uptake in cells and stimulating the liver to convert glucose to glycogen, in which form it can be stored.
Level constancy is accomplished primarily through negative feedback systems