Leukemia

Jacob Georgoulakos and Matthew Lapsley

Definition of Leukemia

Leukemia is a disease in the blood. Leukemia is cancer of the body's blood-forming tissues, including the bone marrow and the lymphatic system.

  • Leukemia comes from the greek roots leukos means white and hermia means blood
  • The roots are talking about the oddly shaped and operating cells
  • It duplicates at an unrestrained and fast pace.
  • Many types of leukemia exist. Some types are more common in children and others in adults

Symptoms of Leukemia How it affects people

The symptoms range and affect areas throughout the body. They weaken your body and affect your overall well-being.

  • Fever or chills
  • Persistent fatigue, weakness
  • Frequent or severe infections
  • Losing weight without trying
  • Swollen lymph nodes, enlarged liver or spleen
  • Easy bleeding or bruising
  • Recurrent nosebleeds
  • Tiny red spots in your skin (petechiae)
  • Excessive sweating, especially at night
  • Bone pain or tenderness
Big image
Figure 1: Swollen Lymph Nodes (Mayo Clinic)

How prevalent is Leukemia

In 2012, there were an estimated 318,389 people living with leukemia in the United States.

Acute Leukemia

  • Irregular blood cells are undeveloped
  • Cells don’t function properly and replicate quickly making the problem worse
  • Powerful and quick treatment is required

Chronic Leukemia

  • Produces too many or not enough cells
  • Associated with older cells
  • Can lie dormant for years

Lymphocytic Leukemia

  • Attacks the lymphoid cells which create the lymphatic tissues that forms the immune system
  • Myelogenous leukemia
  • Affects the myeloid cells
  • Myeloid cells function is to make red blood cells, white blood cells and platelet-producing cells

Other, Rarer Types of Leukemia Exist:

  • Hairy cell leukemia
  • Myelodysplastic syndromes
  • Myeloproliferative disorders
Big image
Figure 2: Top 10 Prevalent Cancers (The National Cancer Institute)

How is Leukemia diagnosed

Figure 3: Physical Exam Image (US News)

Figure 4: Blood Test Image (Medical Daily)

Figure 5: Bone Marrow Test Image (Bone Marrow Biopsy)

Leukaemia: A journey into the body
https://www.youtube.com/watch?v=Qje0fG_JHLY

Video Created By: Sammy Grace

What are the possible causes of Leukemia

  • Artificial radiation
  • benzene and other petrochemicals
  • hair dies
  • People with down syndrome have a higher risk
  • experts say people with certain chromosomal abnormalities
  • Scientist don't know what exactly causes leukemia

What happens at cellular and molecular levels of Leukemia

  • When blood cells acquire mutation in their (DNA)


There may be other changes in the cell but not yet have been fully understood could contribute to leukemia.

Big image
Figure 6 : drugs (Medical news today)

Treatments and Cures

chemotherapy

bone marrow transplant stem cell transplant


The first phase of treatment is the induction phase design to kill leukemia cells in the blood and bone marrow


The second phase is called consolidation/ intensification phase designed to kill the remaining leukemia cells that may be inactive but could begin growing causing leukemia to recur again



The third phase is called the maintenance phase


treatment continues to kill any remaining leukemia remaining at lower dose



There is no cure for leukemia

Works Cited (Matt)

Works Cited (Jacob)

· Hammar, Lawrence. "Leukemia." The Gale Encyclopedia of Science. Ed. K. Lee Lerner and Brenda Wilmoth Lerner. 5th ed. Farmington Hills, MI: Gale, 2014. Science in Context. Web. 16 Dec. 2015.

URL

http://ic.galegroup.com/ic/scic/ReferenceDetailsPage/ReferenceDetailsWindow?failOverType=&query=&windowstate=normal&contentModules=&display-query=&mode=view&displayGroupName=Reference&limiter=&currPage=&disableHighlighting=true&displayGroups=&sortBy=&search_within_results=&p=SCIC&action=e&catId=GALE%7C00000000MX5I&activityType=&scanId=&documentId=GALE%7CCV2644031301&source=Bookmark&u=amhe95753rpa&jsid=e69f390aa9df24c146a30673914effb4


Oberleitner, Melinda Granger, and L. Lee Culvert. "Leukemias, acute." The Gale Encyclopedia of Medicine. Ed. Jacqueline L. Longe. 5th ed. Farmington Hills, MI: Gale, 2015. Science in Context. Web. 17 Dec. 2015.

URL

http://ic.galegroup.com/ic/scic/ReferenceDetailsPage/ReferenceDetailsWindow?failOverType=&query=&prodId=SCIC&windowstate=normal&contentModules=&display-query=&mode=view&displayGroupName=Reference&limiter=&currPage=&disableHighlighting=true&displayGroups=&sortBy=&search_within_results=&p=SCIC&action=e&catId=&activityType=&scanId=&documentId=GALE%7CRUTUTK753302369&source=Bookmark&u=amhe95753rpa&jsid=b975151bf5c534969668b28c29ea10fc


Nordqvist, Christian C. "Lymphoma / Leukemia / Myeloma Cancer / Oncology Leukemia: Causes, Symptoms and Treatments." Medical News Today. MediLexicon International, Wednesday Oct. 2015. Web. 17 Dec. 2015.


http://www.medicalnewstoday.com/articles/142595.php



"Treatment Options." Treatment Options. Seattle Cancer Care Alliance, 2015. Web. 17 Dec. 2015.


http://www.seattlecca.org/diseases/leukemia-children-treatment.cfm




http://www.mayoclinic.org/diseases-conditions/leukemia/basics/causes/con-20024914



http://article.wn.com/view/2015/09/02/Could_Common_Diabetes_Drugs_Help_Fight_Leukemia/


http://www.medicalnewstoday.com/images/articles/270152-drugs.jpg