Hemophilia
What it is?
What is Hemophilia
Hemophilia A
Hemophilia A
is a genetic deficiency in clotting factor VIII, which causes increased bleeding and usually affects males. About 70% of the time it is inherited as an X-linked recessive trait, but around 30% of cases arise from spontaneous mutations.
Hemophilia B
is a blood clotting disorder caused by a mutation of the factor IX gene, leading to a deficiency of factor IX. It is the second-most common form of hemophilia, rarer than hemophilia A. It is sometimes called Christmas disease.
Hemophilia C
is a mild form of haemophilia affecting both sexes. However, it predominantly occurs in Jews of Ashkenazi descent. It is the fourth most common coagulation disorder after hemophilia A and B. In the USA it is thought to affect 1 in 100,000 of the adult population, making it 10% as common as hemophilia A.