Sickle Cell Anemia

and Natural Selection

What is sickle cell anemia?

-You will have abnormal, sticky and stiff red blood cells

-You will have a lower amount of red blood cells in your body

-It is inherited, and a lifelong disease

-usually in people with an African descent

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Natural Selection

-the presence of an allele for sickle-cell anemia prevents people from getting malaria

-If you are homozygous for this allele you will have both alleles of the same sort

-If you are heterozygous for this allele you will have two different alleles

-Survival for the heterozygous, because that allele protects from malaria and can be passed on to future generations

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Anything that causes the genetic structure to change; DNA is damaged or changed; DNA gene is permanently altered

In sickle cell anemia the mutation is caused by the hemoglobin variant Hb S. This will cause the red blood cells to clump together

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Living with Sickle Cell Disease

Our Story: Living with and Managing Sickle Cell Disease (Nicholas H.)