Adenoviridae Party
all adenoviruses welcome
Guest List
Adenoviruses
- medium sized virus (90-100nm)
- no outer lipid membrane, icosohedral virus
- reliant on host cell for survival and replication
- double-stranded DNA
- can carry 22-40 genes
- 49 types that can cause human infection
Transportation
Coming through respiratory means is suggested, but alternatives include oral or fecal routes.
Agenda
12:00- We will gently attach our proteins to to CAR family receptors on the outside of the cell
12:30- Then enter by receptor mediated endocytosis
1:15- Next we will move through the microtubles, heading towards the nucleus
1:30- Our DNA will then enter the nucleus through the pores
2:00- In order to produce new virus particles, our DNA must associate with histone molecules
2:45-Once our viral component has replicated it's put in protein shells and released from the cell
Then we repeat!
Aftermath
Adenoviridae viruses can cause a large range of illnesses. We can create anything from a mild respiratory infection (the common cold) to a severe infection, adenovirus serotype 14 , as a result of our party.
Health Disclaimer
interacting with this virus may result in
- conjunctivitis
- tonsillitis
- ear infection
- pneumonia
- viral meningitis
- hemorrhagic cystitis
- For those with an immunodeficiency it can be fatal