adrenoleukodystrophy

By: Kassidi Spohn

What is it?

Adrenoleukodystrophy is a disorder of peroxisomal fatty acid beta oxidation which results in the accumulation of a very-long chain of fatty acids in tissues throughout the body. The disorder affects the bone marrow and nerve function of a person. It also only affects males b/c it is carried on the X-chromosome.

Features and Effects

Physical features:hyperactive


Emotional features:behavioral problems, aggressive or uninhibited behavioral


Mental features:seizures


Progressive or all at once: progressive


What happens to the lifespan: leading to complete disability or death


Treatments: bone marrow transplant


Limitations: disability


Help at school: difficulty at school, deterioration of handwriting, visual impairment or blindness, difficulty understanding spoken material, decreased understanding of verbal communication.