Ebola Virus

By: Sarah Broder

About the Ebola Virus

Ebola is a rare and deadly disease which is caused by infection with one of the Ebola virus species. Ebola can cause disease in humans and nonhuman primates such as monkeys, gorillas, and chimpanzees.

Symptoms of Ebola

Some symptoms of Ebola include: chills, dehydration, fatigue, fever, loss of appetite, weakness, vomiting, diarrhea, abdominal pain, and serve headaches.


Symptoms for Ebola can appear anywhere from 2 to 21 days after exposure to Ebola. The average amount of days before symptoms start appearing is 8 days.

Causes of Ebola

Ebola is caused by an infection with one of the Ebola virus species.

Immune Cells Involved in Immune Response


Ebola targets several different types of immune cells. Ebola effects Dendritic Cells. Dendritic Cells display signs of an infection, which would infect the t-cells. Since the Dendritic Cells don't give off the correct siginal, the T Cells wouldn't respond to the infection, causing the virus to replicate very quickly.

Ebola Replication

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Ebola Lytic Cycle.


Steps of the Lytic Cycle:

1) Phage attaches onto the host cell and injects DNA.

2) DNA circulates and enters the Lytic Cycle.

3) The phage DNA and proteins are synthesized and assembled into virions.

4) Phage virions are released and reproduction is complete.

Ebola Treatment

There are a series of treatments for the Ebola virus.

  • Providing IV and balancing electrolytes (body salts)
  • Maintaining oxygen status and blood pressure
  • Treating other infections if they occur
  • Oxygen Therapy
  • Blood transfusions
  • Supportive Hospital Care

Prevention

There are ways to prevent from getting the Ebola virus.

  • Practicing careful hygiene
  • Do not handle items that have come in contact with an infected persons blood and body fluids
  • Avoiding contact with bats and nonhuman primates or blood, fluids, and raw meat prepared from these animals
  • After returning, monitor your health for 21 days and seek medical care immediately if you develop symptoms of Ebola