Cancer Research Project
by: Terence Coyle
Clear Cell Renal Cell Carcinoma: Basic Info
Stage 1 is simply a tumor of smaller than 7 cm but only on the kidney, no lymph nodes involved.
Stage 2 is when the tumor grows beyond 7 cm.
The cancer is then qualified for Stage 3 when it reaches any of these requirements: Tumor becomes involved with lymph nodes or veins leading towards the heart. The tumor may also have a fatty substance surrounding it.
The cancer is then on Stage 4 when it has any of the following: The tumor has spread through the fatty tissue. The tumor has become involved with one or more lymph nodes not near the kidneys. Also distant metastasis, meaning cancer being transported to a different part of the body, not connected to the kidneys.
The treatment starts off with many tests and just waiting to see what develops, to see what step they need to take next.
The next option for treatment is surgery, typically removing the entire affected kidney.
The next style of treatment is Targeted Ablative Therapies, essentially, that's specifically locating the tumor and killing the tissues by exposing it to heat or intense cold, both drawing the water out of the tissue.
The final step in treatment of CCRCC would be Targeted Drug Treatments, essentially, building up the body's immune response to cancer cells.
CCRCC's response to chemotherapy and radiology hasn't shown to be very successful. All of these treatments are highly successful but, especially the therapies and drug treatments, have very adverse side affects, that may be fatal. They include: nausea, vomiting, diarrhea, anorexia, coughing, dyspnea (difficulty breathing), hypertension(high blood pressure), intracranial hemorrhage (bleeding into the brain), thrombosis (blood clots) in the brain, rashes, hand foot syndrome, stomatitis, resulting in reduced white blood cells, increasing the risk of infections plus anemia and reduced platelets, impaired kidney function, and fatigue.
Chittoria, Namita, and Brian Rini. "Renal Cell Carcinoma." Renal Cell Carcinoma. Cleveland Clinic, 15 Aug. 2013. Web. 6 Jan. 2016. <http://www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/nephrology/renal-cell-carcinoma/>.
"What Is Kidney Cancer?" What Is Kidney Cancer? The American Cancer Association, 3 Mar. 2015. Web. 6 Jan. 2016. <http://www.cancer.org/cancer/kidneycancer/detailedguide/kidney-cancer-adult-what-is-kidney-cancer>.