Leukemia

Leukemia is...

Leukemia is when your body produces too many white blood cells.



· Too many white blood cells causes abnormal bone marrow growth.

· Bone marrow is exchanged with young and non-different “blast cells”

· “blast cells” are leukocytes

· The tumors are found in bone marrow and lymphoid tissue

· The organs are, liver, spleen, and lymph nodes.

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Sypmtoms

The symptoms of Leukemia are not specific at all.

-fever

-feeling tired

-infections

-headaches

-abnormal weight loss

-rashes

-bone pain

-bloody noses

-bloody gums

-bruising

-feeling bloated

Diagnostics

There are many different test that can be done to determine if you have leukemia.


-Blood test is most common.

-Blood test shows amount of red and whit blood cells,

-More specific test is a bone marrow biopsy.

-A bone in hip or chest is usually used.

-Another type is a spinal tap.

-A thin needle is stuck in the space between vertebra.

-A sample of cerebrospinal fluid is taken.

-Study the cells.

-They are looking for abnormal cells.

Cellular And Molecular Level

The development of leukemia involves a sequential series of mutational events involving primitive cells within the bone marrow.

-Chromosome breakages that have inappropriate gene mutations.

-Mutations usually happen in bone marrow

-Transforms regular cells into mutated cells

-RNA is isolated

-Mutated genes are transfused into cells

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What is leukemia?

Annotation

Hammar, Lawrence. "Leukemia." The Gale Encyclopedia of Science. Ed. K. Lee Lerner and Brenda Wilmoth Lerner. 5th ed. Farmington Hills, MI: Gale, 2014. Science in Context. Web. 22 Dec. 2015


Lawrence Hammar has had extensive training and schooling. He seems to be a very credible source. He attended Johns Hopkins University School of Medicine. He then did an internship at Stanford University. He has won an award for his work. This award was the Kaiser Award for Excellence in Clinical Teaching, Stanford University School of Medicine (1986). Although this is his only text on leukemia, so people could question his knowledge on this specific topic. This source gives detailed information on Leukemia. It gives me the most information compared to other sources. The most helpful detail about this source was the information he gave on the diagnosis.


Works Cited

Hammar, Lawrence. "Leukemia." The Gale Encyclopedia of Science. Ed. K. Lee Lerner and Brenda Wilmoth Lerner. 5th ed. Farmington Hills, MI: Gale, 2014. Science in Context. Web. 22 Dec. 2015.

URL
http://ic.galegroup.com/ic/scic/ReferenceDetailsPage/ReferenceDetailsWindow?failOverType=&query=&prodId=SCIC&windowstate=normal&contentModules=&display-query=&mode=view&displayGroupName=Reference&limiter=&currPage=&disableHighlighting=true&displayGroups=&sortBy=&search_within_results=&p=SCIC&action=e&catId=GALE%7C00000000MX5I&activityType=&scanId=&documentId=GALE%7CCV2644031301&source=Bookmark&u=amhe95753rpa&jsid=4384207aac113e8436ba7cb4ea3e682d

"Leukemia." World of Anatomy and Physiology. Gale, 2010. Science in Context. Web. 22 Dec. 2015.

URL
http://ic.galegroup.com/ic/scic/ReferenceDetailsPage/ReferenceDetailsWindow?failOverType=&query=&prodId=SCIC&windowstate=normal&contentModules=&display-query=&mode=view&displayGroupName=Reference&limiter=&currPage=&disableHighlighting=true&displayGroups=&sortBy=&search_within_results=&p=SCIC&action=e&catId=&activityType=&scanId=&documentId=GALE%7CCV2430500237&source=Bookmark&u=amhe95753rpa&jsid=ba86958ce898ef1d15f6a89e613e2197

"Leukemia." Environmental Encyclopedia. Gale, 2011. Science in Context. Web. 22 Dec. 2015.

URL
http://ic.galegroup.com/ic/scic/ReferenceDetailsPage/ReferenceDetailsWindow?failOverType=&query=&prodId=SCIC&windowstate=normal&contentModules=&display-query=&mode=view&displayGroupName=Reference&limiter=&currPage=&disableHighlighting=true&displayGroups=&sortBy=&search_within_results=&p=SCIC&action=e&catId=&activityType=&scanId=&documentId=GALE%7CCV2644150802&source=Bookmark&u=amhe95753rpa&jsid=25c51cbe77a9559196b0618611ebd00b