Tay Sachs Disorder

By: Isabel Borjas

Tay-Sachs Disorder

An Inherited metabolic disorder in which Certain lipids accumulate in the brain, causing spasticity and health in the childhood.

Symptoms Of Tay-Sachs

  • Deafness
  • Blindness
  • Seizures
  • decreased Muscle Tone
  • Increased Stat-lie response
  • Slow Growth
  • Paralysis or loss of muscle function
  • Red Spot on the macula (an oval-shaped area near the center of the retina in the eye)

Statistics On People With Tay-Sachs

1% Of People for every 27 people suffer from this disorder in the world suffers from this disorder.

Ethnic Group

More Common in a Certain Group?

  • People of eastern European (Ashkenazi) Jewish Descent.
  • Non-Jewish French Canadians living near the St.Lawrence River and in the Cajun community of Louisiana.

How Common is it?

  • Tay-Sachs disease is very rare in the general public, one is 250 people are carriers.
  • One out of 27 Ashkenazi Jew is a carriers
  • Non-Jewish French Canadians living near the St. Lawrence River also have a higher incidence of it.

Famous People With Tay-Sachs

Typically a person with Tay-Sachs dies at a age or 4 or 5. It is possible for a person to develop the symptoms and get this disease later on in life, but less likely. There are no records of famous people with Tay-Sachs Disease.

Treament

No Effective Treatment for Tay-Sachs Disease. Treatment targets controlling some of the symptoms—such as providing anticonvulsants to control seizures—and proper nutrition and hydration as well as other comfort measures.

Cause Of Tay-Sachs

Tay-Sachs Disease is caused by a lack of hexosaminidase A. A protein used to break down a chemical in nerve tissue. These harmful chemicals are caused by ganaliosides, which damage nerve tissue starting in the brain

Cure

  • There is currently no cure like theirs no treatment for Tay sachs disease, though research is going on.
  • There is no alternative to medicine that could temporarily treat the disease.
  • There is no aftermath of this disease. The children don't make it.

Inherit

If both parents are carriers and their child inherit the defective Hex-A gene from each of them, the child will have Tay-Sachs disease When both parents are carriers of the defective Tay-Sachs gene, each child has a 25 percent chance of having Tay Sachs disease and a 50 percent chance of being a carrier
Nathan's Story; Tay-Sachs Disease in the Irish Population