Acute Intermittent Porphyria

By Brandi

About AIP

AIP was discovered by Gerardus Johannes Mulder in 1844. People get this disease by a mutation in the heme and it impacts the nervous system. Sometimes people can go without even knowing they have AIP. Usually, AIP needs something to activate its symptoms like a changed diet or drugs.

Who gets AIP?

5 in 100,000 people get this disease and men and women get it equally. There aren't any ethnic groups that specifically receive this disorder.

Signs/Symptoms

Symptoms for this disease may never be present.


  • Abdominal Pain
  • Nausea
  • Constipation
  • Pain in the back, arms, and legs
  • Muscle weakness
  • Urinary Retention
  • Palpitation
  • Confusion, hallucinations, seizures

Prognosis

Most of the time, AIP is caught early and recovery doesn't take very long. When it is caught late, it can take years for the muscle to recover. Most people recover completley

Treatments

Pain and nausea medication along with IV hydration is given to patients when they first get to the hospital. After they are diagnosed, the patients are given carbohydrates like glucose to help stop the disease. When the carbohydrates aren't enough, Panhematin (a medication helps put more heme in your system).

Pedigree of Acute Intermittent Porphyria

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