Sickle cell disease (SCD) usually manifests early in childhood. For the first 6 months of life, infants are protected largely by elevated levels of Hb F; soon thereafter, the condition becomes evident.
Pain crises constitute the most distinguishing clinical feature of sickle cell disease and are the leading cause of emergency department visits and hospitalizations for affected patients.
Name and Background
Sickle Cell Anemia also known as Hemoglobin S
November 1910, Dr. James Herrick made the first description in published literature of the sickle cell disease.A blood test can check for hemoglobin S — the defective form of hemoglobin that underlies sickle cell anemia. In the United States, this blood test is part of routine newborn screening done at the hospital.
Red Blood Cells are misshaped and break down.