Lou Gehrig's Disease (ALS)

Biology Research Project

Lou Gehrig's Disease

I chose to research this disease because it effected a great baseball player. And I want to know how this disease effected him physically.


Neurons in the body breakdown and die, which leaves the body weak.

The entire body is at risk when you have ALS

Lou Gehrig's Disease - Effects of Lou Gehrig's Disease - What Is ALS Video.mp4

Amyotrophic Lateral Sclerosis (ALS)

Symptoms include:

  1. Difficulty Walking (Clumsy)
  2. Weakens Legs and Ankles
  3. Slurring of speech
  4. Trouble swallowing
  5. Muscle cramps and spasms
  6. Difficult to hold head up or keep good posture


Since ALS does not have a cure, doctors focus on slowing down the disease. You might want to have therapy for anything to slow down the disease is improving your quality of life.


There are 3 possible causes for ALS

  1. Gene Mutation- Mutation of the genes could lead too the inheritance of ALS
  2. Chemical Imbalance- people with ALS have high levels of glutamate. The chemical messenger to the brain. to much of this is poisonous to nerves.
  3. Disorganized Immune Response- The Immune system begins attacking its self which leads to damaged neurons and dead nerves

ALS is inherited in 5 to 10 percent of cases, but most of the time it occurs randomly.

ALS - Lou Gehrig's disease


ALS is hard to discover at the early stages since it looks similar to many other neurological diseases. But Test may include...

  1. Electromyogram (EMG)
  2. Nerve conduction study
  3. Magnetic resonance imaging (MRI)
  4. Blood and Urine Test
  5. Spinal tap (lumbar puncture)
  6. Muscle biopsy

Population Effects

  • Less Than 20,000 people a year get this disease.
  • 5,600 people in the US get diagnosed with ALS
  • 93% of the people that have ALS are White, 60% are men.
  • Most People develop ALS during the age of 40 to 70
  • 50% of people that get ALS live for About 3 years after diagnoses.
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What I Discovered

  • The smartest man in the world has ALS.
  • That most people don't live to long after diagnoses.