Severe Combined Immunodeficiency

Deanna Dautrich

What is it?

Severe Combined ImmuneDeficiency is a very rare and inherited disorder that affects your immune system. Unfortunately, this makes you more vulnerable to dangerous bacteria and viruses a normal immune system could fight off. Not to mention, more prone to contract disease.

1 out of every 100,000 babies is born with SCID.

How is it passed down?

Only the "x" chromosome can be a carrier of SCID, so likelihood of males inheriting this disease is more common than females. In order for a girl to receive SCID, both parents must carry the gene. However, for a guy to inherit SCID, Only one parent must carry the gene.

SCID is sometimes called Bubble Boy disease because one boy, who was affected, had to live in a plastic bubble for 12 years

Is it treatable?

Fortunately, the answer is yes! A bone marrow transplant from your sibling, with similar genetic makeup, is the most effective and successful.

How does treatment work?

Stem cells are taken from the bone marrow of a healthy donor and injected into the SCID patient, which will then stimulate the production of the needed immune cells.

Gene therapy for this disorder may soon be possible. This therapy would compensate for the faulty gene by injecting healthy copies of the gene into a patient's bone marrow stem cells.