Clostridium Difficile

Christin Apple

AKA: C. Diff. Colitis

Inflammation of the colon caused by the bacteria Clostridium difficile.


requires a medical diagnosis and lab tests and imaging.

How is the disease transmitted?

It can be spread from person to person by spores, touching a contaminated surface or contaminated food or water.

relative frequency

data suggest that C. difficile may be frequently encountered in specimens obtained from patients with diarrhea who receive antibiotics and may play a role in diarrheal disease in such patients.

disease course

C. difficile affects disease course of IBD in several ways, including triggering disease flares, sustaining activity, and in some cases, acting as an “innocent” bystander.

possible complications


acute kidney failure

perforated colon



Treatment includes antibiotics. In rare cases, fecal transplant or surgery may be needed.