Hepatitis A research

By: Jadyan, Maya, Chris, and Kevin

How can i get it, and how can i prevent it?

Hepatitis A is preventable by vaccine. It spreads from contaminated food or water, or contact with someone who is infected.The hepatitis A vaccine is typically given in two doses — initial vaccination followed by a booster shot six months later.


If you're traveling in regions where hepatitis A outbreaks occur, peel and wash all fresh fruits and vegetables yourself and avoid raw or undercooked meat and fish. Drink bottled water and use it when brushing your teeth. Don't drink beverages of unknown purity, with or without ice. If bottled water isn't available, boil tap water before drinking it.

What are the causes? Immune cells?

The hepatitis A virus, which causes the infection, usually is spread when a person ingests even tiny amounts of contaminated fecal matter. The hepatitis A virus infects liver cells and causes inflammation.


The inflammation can impair liver function and cause other signs and symptoms of hepatitis A. The immune cells that are involved in fighting this virus are the adaptive cells

How do i know that i have it? What are the symptoms?

Symptoms include fatigue, nausea, abdominal pain, loss of appetite, and low-grade fever.

The condition clears up on its own in one or two months. Many people with HAV infection have no symptoms at all. People who do not have symptoms can still spread the virus so it is difficult to know when a person has been exposed to the virus.


Symptoms of hepatitis A usually develop between 2 and 6 weeks after infection. The symptoms are usually not too severe and go away on their own.

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How can this virus be treated?

The condition clears up on its own in one or two months. Rest and adequate hydration can help. There are no specific medicines to cure infection with hepatitis A. Most people require no treatment except to relieve symptoms. However, if symptoms become severe or dehydration develops, the person should seek medical care Fast!
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How does this virus replicates?

After entry into the host cell, the virus loses the capsid and the uncoated RNA induces the host cell to produce the viral polyprotein without shutting off the protein synthesis of the cell. Among the viral proteins there is a protease for the synthesis of structural proteins and a polymerase for the replication of viral RNA which becomes rapidly encapsidated into new viruses.
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What are the steps in the process?

1: The virus attaches to the cell.


2: Dna is inserted into the cell.


3: Viral DNA forms a circle inside the host cell's DNA


4: The viral DNA becomes or attaches to the DNA of the hosts.


5:The host cell replicates by mitosis (any new cell has viral DNA in it)


6: Viral DNA pinches off the host cell's DNA and forms a circle


7: The lytic cycle is initiated therefore killing the cell.

Vaccines

Vaccines are available for long-term prevention of HAV infection in persons 1 year of age and older. Good personal hygiene and proper sanitation can also help prevent the spread of hepatitis A.


Hepatitis A vaccine is a vaccine that prevents hepatitis A. It is effective in around 95% of cases and lasts for at least fifteen years and possibly a person's entire life. If given, two doses are recommended beginning after the age of one. It is given by injection into a muscle.

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