Turner Syndrome

Jessica Allen

What is Turner Syndrome?

Turner Syndrome is when a girl is missing or partially missing an X chromosome. Turner syndrome is also one of the most common sex chromosome disorder found in females. Turner syndrome is due to the presence of only on normal X chromosome and no other normal sex chromosome. Males can not get this disease because their sex chromosomes are XY so if they were missing an X chromosome it wouldn't make sense as a female's sex chromosomes are XX or just X.


Below represents what someone with Turner syndrome chromosomes would look like, if you notice in the bottom under X there is only half of the X chromosome.

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Symptoms of Turner Syndrome...

Symptoms of Turner syndrome can vary significantly. Some symptoms for young women or teens are no growth spurts, learning disabilities, and failure to begin sexual changes that happen during puberty. For newborns some symptoms are wide or web-like neck, small lower jaw, low set ears, low hairline(at back of head), short fingers or toes, and delayed growth. For babies who have not been born yet some symptoms which can be found during an ultrasound are large fluid collection on back of neck, heart abnormalities, and abnormal kidneys.

Inheritance...

Most cases of Turner syndrome is not inherited, which means the chromosomal abnormality occurs randomly during the formation of reproductive cells(sperm and egg) in the effected person's parents. Can result in reproductive cells with an abnormal number of chromosomes. Which means the child will have a single X chromosome in each cell and will be missing the other sex chromosome. On rare occasions Turner syndrome caused by a partial deletion of the X chromosome can be passed from one generation to the next.

Cause...

Turner Syndrome is caused by a missing or incomplete X chromosome. Some of the genes on the X chromosome are involved in growth and sexual development, which is why girls with the disorder are shorter than normal and have incompletely developed sexual characteristics. Turner syndrome can also be caused by nondisjunction. Nondisjunction happens when a pair of sex chromosomes fails to separate during formation of a sperm or egg. When a sperm with no X chromosomes unites with a normal egg to from an embryo, the embryo will have just one X chromosome. When the embryo grows and the cell divides, the X chromosome will be missing in every cell in the baby's body.

People affected...

Turner syndrome occurs in about 1 in 2500 newborn girls worldwide, but are much more common among pregnancies that do not survive to term due to miscarriages and stillbirths.

Some people who have Turner syndrome are Missy Marlowe who is a world championship gymnast, Linda Hunt who is a actress especially known for being on NCIS, and Jannet Cranky who is a Scottish actress known for being on The Krankies Klub.


Below represents a graph of the growth rate of people with Turner syndrome, red being people with Turner syndrome,

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Treatments...

The primary treatments for nearly all girls and women include hormone therapies include growth hormones and estrogen therapy. Somethings that are important fro a female with turner syndrome is to have regular check up doctor, periodic follow up with heart specialist, and have healthy lifestyle habits.