a rare malignant tumor of the retina, in young children
When discovered and who:
The symptoms and side effects:
The late effects can include:
~loss of vision in eyes
~reduced kidney function
~slowed or delayed growth or development
~increased risk of other cancers
What tests are done to see if an individual has retinoblastoma
~usually found when a child is brought to a doctor because they have certain signs or symptoms
~if you have the signs of this the doctor will examine there eyes and get a complete medical history
~if suspected the doctor will refer you to an ophthalmologist-doctor who specializes in eye diseases
~imaging tests are done to help confirm
this is a: shrunken eye and red
this is: a squint, where one eye looks in or out
this is a: white reflection in the pupil
~Cure search for Children's Cancer
~NORD, National Organization for Rare Disorders
Anyway to prevent retinoblastoma or treatments
There are no ways to prevent this because it is so rare.
Some treatments are:
How retinoblastoma is inherited
~60% of retinoblastomas are non-germinal, means can not be inherited
~per year 250-350 children are diagnosed in the U.S, accounts for about 4% of all cancers in children younger than 15
~this gene is located on region of the long(q) arm of chromosome 13
~RB1-retinoblastoma 1, provides instructions for making a protein called pRB, acts as a tumor suppression meaning it regulates cell growth and keeps cells from dividing to fast or in an uncontrolled way
~ more likely to occur in early childhood, younger the 5 years old
Doctors that work in this field:
Ophthalmologist: Specializes in eye diseases.
Oncologist: Specializes in cancer.
Pediatric hematologist-oncology: Treats blood disorders and cancer in children.
Medical geneticist: Diagnoses and manages hereditary disorders.
Pediatrician: Provides medical care for infants, children, and teenagers.
Primary care provider (PCP): Prevents, diagnoses, and treats diseases.